A B C D E F G H I J K L M N O P Q R S T U V W X Y Z in Japanese


Abe E, Hayashi Y, Hama Y, Hayashi M, Inagaki M, Ito M. (2006) A novel phosphatidylcholine which contains pentadecanoic acid at sn-1 and docosahexaenoic acid at sn-2 in Schizochytrium sp. F26-b.  J Biochem 140: 247-253

Abril JR, Barclay WR, Abril PG (2000) Safe use of microalgae (DHA GOLDTM) in laying hen feed for the production of DHA-enriched eggs.  In: Sim JS, Nakai S, Guenter W (Eds) Egg Nutrition and Biotechnology.  CAB International, Wallingford, pp. 197–202

Abril R, Garrett J, Zeller SG, Sander WJ, Mast RW (2003) Safety assessment of DHA-rich microalgae from Schizochytrium sp. Part V: target animal safety/toxicity study in growing swine.  Regul Toxicol Pharmacol 37(1): 73-82

Adl SM, Simpson AGB, Farmer MA, Andersen RA, Anderson OR, Barta JR, Bowser SS, Brugerolle G, Fensome RA, Frederico S, James TY, Karpov S, Kugrens P, Krug J, Lane CE, Lewis LA, Lodge J, Lynn HD, Mann DG, Mccourt RM, Mendoza L, Mosterup O, Mozley-Standridge SE, Nerad TA, Shearer CA, Smirnov AV, Spiegel FW, Taylor MFJR (2005) The new higher-level classification of eukaryotes with emphasis on the taxonomy of protists.  J Eukaryot Microbiol 52: 399-451

Aki T, Hachida K, Yoshinaga M, Katai Y, Yamasaki T, Kawamoto S, Kakizono T, Maoka T, Shigeta S, Suzuki O, Ono K (2003) Thraustochytrid as a potential source of carotenoids.  J Am Oil Chem Soc 80: 789-794

Aki T, Suzuki O (2001) Biosnsthesis of polyunsaturated fatty acids in Labyrinthula.  Aquabiology 23: 46-51 (in Japanese)

Alderman DJ, Harrison JL, Bremer GB, Jones EBG (1974) Taxonomic revisions in the marine biflagellate fungi. The ultrastructural evidence.  Marine Biol 25: 345-357

Alderman DJ, Jones EBG (1971) Physiological requirements of two marine phycomycetes, Althornia crouchii and Ostracoblabe implexa.  Trans Br mycol Soc 57: 213-225

Alderman DJ, Polglase JL (1986) Are fungal diseases significant in the marine environment? In Moss ST (Ed) The Biology of Marine Fungi. Cambridge University. Press, London, UK, pp. 189-198

Amon JP, French KH (2004) Photoresponses of the marine protist Ulkenia sp. zoospores to ambient, artificial and bioluminescent light.  Mycologia 96: 463-469

Amon JP, Perkins FO (1968) Structure of Labyrinthula sp. zoospores.  J protozool 15: 543-546

Anderson RS, Kraus BS, McGladdery SE, Reece KS, Stokes NA (2003) A thraustochytrid protist isolated from Mercenaria mercenaria: molecular characterization and host defense responses.  Fish Shellfish Immunol 15: 183-194

Anbu P, Kim DU, Jeh EJ, Jeong YS, Hur BK (2007) Investigation of the physiological properties and synthesis of PUFAs from thraustochytrids and its electrophoretic karyotypes.  Biotechnology and Bioprocess Engineering 12: 720-729

Armenta RE, Burja A, Radianingtyas H, Barrow CJ (2006) Critical assessment of various techniques for the extraction of carotenoids and Co-enzyme Q10 from the thraustochytrid strain ONC-T18.  J Agric Food Chem 54: 9752–9758

Ashford A, Barclay WR, Weaver CA, Giddings TH, Zeller S (2000) Electron microscopy may reveal structure of docosahexaenoic acid-rich oil within Schizochytrium sp.  Lipids 35: 1377–1386

Azevedo C, Corral L (1997) Some ultrastructural observations of a thraustochytrid (Protoctista, Labyrinthulomycota) from the clam Ruditapes decussatus (Mollusca, Bivalvia).  Diseases of Aquatic Organisms 31: 73-78

Arment RE, Burja A, Radianingtyas H, Barrow CJ (2006) Critical assessment of various techniques for the extraction of carotenoids and co-enzyme Q10 from the thraustochytrid strain ONC-T18.  J Agric Food Chem 54: 9752-9758

Armstrong E, Rogerson A, Leftley JW (2000) Utilisation of seaweed carbon by three surface associated heterotrophic protists, Stereomyxa ramosa, Nitzschia alba and Labyrinthula sp.  Aquat Microb Ecol 21: 49-57

Artemtchuk NJ (1972) The fungi of the White Sea. III. New phycomycetes,discovered in the great Salma Strait of the Kandalakshial Bay. Veröff lnst Meeresforsch Bremerh 13: 231-237

Ashford A, Barclay WR, Weaver CA, Giddings TH, Zeller S (2000) Electro Microscopy May Reveal Structure of Docosahexaenoic Acid-Rich Oil Within Schizochytrium sp. Lipids 35: 1377-1386

Athalye SK, Garcia RA, Wen Z (2009) Use of biodiesel-deviced crude glycerol for producing eicosapentaenoic acid (EPA) by the fungus Pythium irregulare.  J Agric Food Chem 57: 2739-2744

Augustyn OPH, Kogk JLF, Ferreira D (1990) Differentiation between yeast species, and strains within a species, by cellular fatty acid analysis. 3. Saccharomyces sensu lato, Arxiozyma and Pachytichospora. System Appl Microbiol 13: 44-55

Awaji M, Machii A, Nakamura HK, Wada KT (1989) Characterization of a zoosporic fungus appearing in primary cultures of the Kuruma Prawn Midgut Gland.  Bull Natl Res Inst Aquaculture 15: 19-27

Azevedo C, Corral L (1997) Some ultrastructural observations of a thraustochytrid (Protoctista, Labyrinthulomycota) from the clam Ruditapes decussates (Mollusca, Bivalvia).  Dis Aquat Org 31: 73-78 <PDF>


Bahnweg G (1979a) Studies on the physiology of thraustochytriales I. Growth requirements and nitrogen nutrition of Thraustochytrium spp., Schizochytrium sp., Japoochytrium sp., Ulkenia spp., and Labyrinthuloides spp. Veröff Inst Meeresforsch Bremerhaven  17: 245–268

Bahnweg G (1979b) Studies on the physiology of thraustochytriales II. Carbon nutrition of Thraustochytrium spp., Schizochytrium sp., Japoochytrium sp., Ulkenia spp., and Labyrinthuloides spp.  Veröff Inst Meeresforsch Bremerhaven 17: 269–273

Bahnweg G, Sparrow FK (1972) Aplanochytrium kerguelensis gen. nov. spec. nov., a new phycomycete from subantarctic marine waters.  Arch Mikrobiol 81: 45-49

Bahnweg G, Sparrow FK (1974a) Four new species of Thraustochytrium from antartic regions, with notes on the distribution of zoosporic fungi in the anatric marine ecosystems.  Amer J Bot 61: 754-766

Bahnweg G, Sparrow FK (1974b) Occurrence, distribution and kinds of zoosporic fungi in subantarctic and Antarctic waters. Veroff Inst. Meeresforsch Bremerh Suppl 5: 149-157.

Bailey RB, DiMasi D, Hansen JM, Mirrasoul PJ, Ruecker CM, Veeder III, George T, Kaneko T, Barclay WR (2003) Enhanced production of lipids containing poloyunsaturated fatty acids by very high density cultures of eukaryotic microbes in fermentors. United States Patent 6,607,900

Bajpai PK, Bajpai P, Ward OP (1991) Optimization of production of docosahexaenoic acid (DHA) by Thraustochytrium aureum ATCC 34304.  J Am Oil Chem Soc 68: 509–514

Bajpai P., Bajpai P. K., Ward O. P. (1991) Production of docosahexaenoic acid by Thraustochytrium aureum. Appl Microbiol Biotechnol 35: 706-710

Barclay WR (1994a) Food product having high concentrations of omega-3 highly unsaturated fatty acids. US Patent 5,340,594

Barclay WR (1994b) Process for growing Thraustochytrium and Schizochytrium using non-chloride salts to produce a micro-floral biomass having omega-3 highly unsaturated fatty acids. US Patent 5,340,742

Barclay W, Zeller S (1996) Nutritional enhancement of n-3 and n-6 fatty acids in rotifers and Artemia nauplii by feeding spray-dried Schizochytrium sp.  J World Aquac Soc 27: 314–322

Barclay WR, Weaver C, Metz J (2005) Development of a docosahexaenoic acid production technology using Schizochytrium: a historical perspective.  In: Cohen Z, Ratledge C (Eds) Single cell oil. AOCS, Champaign, Illinois, pp. 36– 47

Barr DJ (1981) The phylogenetic and taxonomic implications of flagellar rootlet morphology among zoosporic fungi.  BioSystems 14(3): 359-370

Barr DJS, Allan PME  (1985) A comparison of the flagellar apparatus in Phytophthora, Saprolegnia, Thraustochytrium, and Rhizidiomyces. Can J Bot 63: 138-154.

Barr DJS (1992) Evolution and Kingdoms of organisms from the perspective of a mycologist. Mycologia 84: 1-11.

Bartsch G (1971) [Cytologic studies of Labyrinthula coenocystis Schmoller in different culture conditions] Z Allg Mikrobiol 11(2): 79-90

Battaglene SC, Seymour JE, Ramofafia C, Lane I (2002) Spawning induction of three tropical sea cucumbers, Holothuria scabra, H. fuscogilva and Actinopyga mauritiana.  Aquaculture 207: 29-47 <Link>

Belsky MM, Goldstein S (1964) Glucose matabolism of Thraustochytrium roseum, a nonfilamentous marine phycomycete.  Arch Mikrobiol 49: 375-382

Bent E, Loffredo A, Yang JI, McKenry MV, Becker JO, Borneman J. (2009) Investigations into peach seedling stunting caused by a replant soil.  FEMS Microbiol Ecol 68(2): 192-200

Bigelow DM, Olsen MW, Gilbertson RL (2005) Labyrinthula terrestris sp. nov., a new pathogen of turf grass. Mycologia 97: 185-190 <PDF>

Boeckaert C, Fievez V, Van Hecke D, Verstraete W, Boon N (2007) Changes in rumen biohydrogenation intermediates and ciliate protozoa diversity after algae supplementation to dairy cattle.  European Journal of Lipid Science and Technology 109(8): 767-777

Boeckaert C, Vlaeminck B, Dijkstra J, Issa-Zacharia A, Van Nespen T, Van Straalen W, Fievez V. (2008) Effect of dietary starch or micro algae supplementation on rumen fermentation and milk fatty acid composition of dairy cows.  J Dairy Sci 91(12): 4714-4727  <Link>

Boenigk J, Arndt H (2002) Bacterivory by heterotrophic flagellates: community structure and feeding strategies.  Antonie van Leewenhoek 81: 465–480.

Bongiorni L, Dini F (2002) Distribution and abundance of thraustochytrids in different Mediterranean coastal habitats.  Aquatic Microbial Ecology 30: 49-56

Bongiorni L., Dini F. (2004) Thraustochytrids, fungoid protists in mediterranean sandy shores. Marine Biotechnology 6 : 71-75

Bongiorni L, Jain R, Raghukumar S, Aggarwal RK (2005) Thraustochytrium gaertnerium sp. nov.: a new thraustochytrid stramenopilan protist from mangroves of Goa, India. Protist 156: 303-315

Bongiorni L, Mirto S, Pusceddu A, Danovaro R. (2005) Response of benthic protozoa and thraustochytrid protists to fish farm impact in seagrass (Posidonia oceanica) and soft-bottom sediments.  Microb Ecol 50(2): 268-276

Bongiorni L, Pignataro L, Santangelo G (2004) Thraustochytrids (fungoid protists): an unexplored component of marine sediment microbiota.  Scientia Marina 68(supp. 1): 43-48

Bongiorni L, Pusceddu A, Danovaro R (2005) Enzyme activities of epiphytic and benthic thraustochytrids involved in organic matter degradation. Aquat. Microb. Ecol. 41: 299-305.

Booth T, Miller CE (1968) Comparative morphological and taxonomic studies in the genus Thraustochytrium. Mycologia. 60: 480-496

Booth T, Miller CE (1969) Morphological development of an isolate of Schizochytrium aggregatum.  Can J Bot 47: 2051-2054

Bower SM (1987) Labyrinthuloides haliotidis n. sp. (Protozoa: Labyrinthumorpha), a pathogenic parasite of small, juvenile abalone in a British Columbia mariculture facility.  Can J Zool 65: 1996–2007

Bower SM, McLean N, Whitaker DJ (1989a) Mechanism of infection by Labyrinthuloides haliotidis (Protozoa: Labyrinthomorpha).  J Invertebr Pathol 53: 401-409.

Bower SM, Whitaker DJ, Voltolina D (1989b) Resistance to ozone of zoospores of the thraustochytrid abalone parasite, Labyrinthuloides haliotidis (Protozoa: Labyrinthomorpha). Aquaculture 78: 147-152.

Bowles RD, Hunt AE, Bremer GB, Duchars MG, Eaton RA (1999) Long-chain n-3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimization of docosahexaenoic acid production. J Biotechnol 70: 193-202

Bremer GB (1995) Lower marine fungi (labyrinthulomycetes) and the decay of mangrove leaf litter. Hydrobiologia 295: 89-95 <PDF>; erratum <PDF>

Bremer G.B. and Talbot G. (1995): Cellulolytic enzyme activity in the marine protist Schizocbytrium aggregatum.  Bot. Mar. 38, 37-41

Bugge DM, Allam B (2007) Effects of starvation and macroalgae extracts on the survival and growth of quahog parasite unknown (QPX).  J Exp Mar Biol Ecol 348: 60–69.

Bumpus SB, Magarvey NA, Kelleher NL, Walsh CT, Calderone CT (2008) Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis.  J Am Chem Soc 130: 11614–11616.  <Link>

Burja AM, Armenta RE, Radianingtyas H, Barrow CJ (2007) Evaluation of fatty acid extraction methods for Thraustochytrium sp. ONC-T18.  J Agric Food Chem 55(12): 4795-4801

Burja AM, Radianingtyas H, Windust A, Barrow CJ (2006) Isolation and characterization of polyunsaturated fatty acid producing Thraustochytrium species: screening of strains and optimization of omega-3 production.  App Microbiol Biotechnol 72: 1161–1169


Carmona ML, Naganuma T, Yamanoka Y (2003) Identification by HPLC-MS carotenoids of the Thraustochytrium CHN-1 strain isolated from the Seto Island Sea. Biosci Biotechnol Biochem 67: 884-888

Carter CG, Bransden MP, Lewis TE, Nichols PD (2003) Potential of thraustochytrids to partially replace fish oil in Atlantic salmon feeds. Mar Biotechnol (NY) 5(5): 480-492

Carter CG, Lewis TE, Nichols PD (2003) Comparison of cholestane and yttrium oxide as digestibility markers for lipid components in Atlantic salmon (Salmo salar L.) diets. 
Aquaculture 225: 341-351

Cathrine SJ, Raghukumar C (2009) Anaerobic denitrification in fungi from the coastal marine sediments off Goa, India. Mycol Res 113: 100-109  <Link>

Cavalier-Smith T (1998) A revised six-kingdom system of life. Biol. Rev. 73, 203–266.

Cavalier-Smith T (1997) Sagenista and Bigyra, two phyla of heterotrophic heterokont Chromists. Archiv für Protistenkunde 148: 253-267

Cavalier-Smith T, Allsopp MTEP (1996) Corallochytrium, an enigmatic non-flagellate protozoan related to choanoflagellates. Europ J Protistol 32: 306-310

Cavalier-Smith T, Allsopp MTEP, Chao EE (1994) Thraustochytrids are chromists, not fungi: 18S r RNA signature of Heterokonta. Phil Trans R Soc Lond B Biol Sci 346: 387–397

Cavalier-Smith T, Chao EEY (2006) Phylogeny and megasystematics of phagotrophic heterokonts (Kingdom Chromista).  J Mol Evol 62: 388–420

Cejp (1959)

Chakraborty DK (1974) On the ecology of the infection of the marine diatom Coscinodiscus granii by Lagenisma coscindisci in the Weser estuary. Veroff Inst. Meeresforsch. Bremerh. Supplement 5: 115-122

Chamberlain AHL (1980) Cytochemical studies on the cell walls of Thraustochytrium spp.  Bot Mar 23: 669–677

Chamberlain AHL, Moss ST (1988) The thraustochytrids: a protist group with mixed affinities.  BioSystems 21: 341-349

Chen JQ, Jiang XZ, Liu LX, Huang JZ (2007) Expression of Thraustochytrium sp. FJN-10 Delta ^4-Desaturase Gene in Saccharomyces cerevisiae.  Microbiology (Beijing) 34(6): 1154-1157

Chen LZ (2009) Production of Docosahexaenoic Acid by Fed-batch Cultivation of Schizochytrium sp.  Xiamen University Natural Science 48(1): 88-93

Chen SF, Chien CY (2002) Six proliferous species of Thraustochytrium from Taiwan.  Taiwania 47: 106-114.  <PDF>

Chi Z, Hu B, Liu Y, Frear C, Wen Z, Chen S (2007) Production of omega-3 polyunsaturated fatty acids from cull potato using an algae culture process.  Appl Biochem Biotechnol 137-140(1): 805-815

Chi Z, Liu Y, Frear C, Chen S (2009) Study of a two-stage growth of DHA-producing marine algae Schizochytrium limacinum SR21 with shifting dissolved oxygen level. Appl Microbiol Biotechnol 81(6): 1141-1148

Chi Z, Pyle D, Wen Z, Frear C, Chen S (2007) A laboratory study of producing docosahexaenoic acid from biodiesel-waste glycerol by microalgal fermentation.  Process Biochem 42: 1537-1545  <Link>

Chin HJ, Shen TF, Su HP, Ding ST (2006) Schizochytrium limacinum SR-21 as a source of docosahexaenoic acid: optimal growth and use as a dietary supplement for laying hens.  Australian Journal of Agricultural Research 57(1): 13-20

Cho DW, Song SK, Kim WH, Hur BK (2005) Effect of Operating Factors on the Growth and DHA Biosynthesis of Thraustochytrium aureum ATCC 34304.  Korean Journal of Microbiology and Biotechnology 33(1): 51-55

Cienkowski L (1867) Über den Bau und die Entwickelung der Labyrinthuleen. Arch Mikrosk Anat 3: 274-310 <Link>

Cohen Z, Ratleldge C (2005) Single cell oil. AOCS, Champagne, Illinois

Colaco A, Raghukumar C, Mohandass C, Cardigos F, Santos RS (2006) Effect of shallow-water venting in Azores on a few marine biota.  Cah Biol Mar 47: 359–364

Coleman NK, Vestal JR (1987) An epifluorescent microscopy study of enzymatic hydrolysis of fluorescein diacetate associated with the ectoplasmic net elements of the protist Thraustochytrium striatum.  Can J Microbiol 33: 841–843  <Link>

Cox SL, Hulston D, Maas EW (2009) Cryopreservation of marine thraustochytrids (Labyrinthulomycetes).  Cryobiology (in press)

Cox B, Mackin J (1974) Studies on a new species of Labyrinthula (Labyrinthulales) isolated from the marine gastropod Thais haemastoma floridana. Trans. Am. Micr* Soc* 93: 62-70.

Craven KD, Peterson PD, Windham DE, Mitchell TK, Martin SB (2005) Molecular identification of the turf grass rapid blight pathogen. Mycologia 97: 160–166


Dahl SF, Perrigaulta M, Allam B (2008) Laboratory transmission studies of QPX disease in the hard clam: Interactions between different host strains and pathogen isolates.  Aquaculture 280: 64-70

Damare V, Raghukumar S (2008) Abundance of thraustochytrids and bacteria in the equatorial Indian Ocean, in relation to transparent exopolymeric particles (TEPs). FEMS Microbiol Ecol 65(1): 40-49

Damude HG, Kinney AJ (2007) Engineering oilseed plants for a sustainable, land-based source of long chain polyunsaturated fatty acids. Lipids 42:179–185

Dang DH, Nakahara T (2008) Comparison of Labyrinthulid Strains L4 and L75 by Fatty Acid Composition and Characteristics.  Journal of Fisheries Science and Technology  11(3): 149-158

Darley WM, Porter D, Fuller MS (1973) Cell wall composition andsynthesis via Golgi-directed scale formation in the marine eukaryote, Schizochytrium aggregatum, with a note on Thraustochytrium sp. Arch. Mikrobiol. 90: 89–106

den Hartog C., Vergeer L.H.T. and Rismondo A.F. (1996): Occurrence of Labyrintbula zosterae in Zostera marina from Venice Lagoon. Bot. Mar. 39, 23-26.

Diez B, Pedros-Alio C, Marsh TL, Massana R (2001) Application of denaturing gradient gel electrophoresis (DGGE) to study the diversity of marine picoeukaryotic assemblages and comparison of DGGE with other molecular techniques. Appl Environ Microbiol 67(7): 2942-2951

Douhan GW, Olsen MW, Herrell A, Winder C, Wong F, Entwistle K (2009) Genetic diversity of Labyrinthula terrestris, a newly emergent plant pathogen, and the discovery of new Labyrinthulid organisms. Mycol Res (in press)

Dove ADM, Bowser PR, Cerrato RM (2004) Histological analysis of an outbreak of QPX disease in hard clams Mercenaria mercenaria in New York.  J Aquat Anim Health 16: 246–250.

Dufosse L, Galaup P, Yaron A, Malis-Arad S, Blanc P, Chidrambara-Murthy K, Ravishankar G (2005) Microorganisms and microalgae as sources of pigments for food use: a scientific oddity or an industrial reality? Trends Food Sci Technol 16:389–406

Dykova I, Fiala I, Dvorakova H, Peckova H (2008) Living together: the marine amoeba Thecamoeba hilla Schaeffer, 1926 and its endosymbiont Labyrinthula sp. Eur J Protistol 44(4): 308-316


Ellenbogen B, Aaronson S, Goldstein S, Belsky M (1969) Polyunsaturated fatty acids of aquatic fungi: possible phylogenetic significance.  Comp Biochem Physiol 29: 805-811

Elston RA (????) Other diseases, other molluscs.  <PDF>

Entwistle CA, Olsen MW, Bigelow DM (2006) First report of a Labyrinthula spp. causing rapid blight of Agrostis capillaris and Poa annua on amenity turfgrass in the UK.  Plant Pathlogy 55(2): 306-306


Fan KW, Chen F (2007a) Production of high-value products by marine microalgae thraustocytrids. In: Yang S-T (ed) Bioprocessing for value-added products from renewable resources. New Technologies and Applications. Amsterday, Elsevier, pp 293–324

Fan KW, Chen F, Jones EGB, Vrijmoed LLP. (2001) Eicosapentaenoic and docosahexaenoic acids production by and okara-utilizing potential of thraustochytrids. Journal of Industrial Microbiology & Biotechnology 27: 199-202  <Link>

Fan KW, Jiang Y, Faan Y-W, Chen F (2007b) Lipid characterization of mangrove thraustochytrid―Schizochytrium mangrovei. J Agric Food Chem 55:2906–2210

Fan KW, Jiang Y, Ho LT, Chen F (2009) Differentiation in fatty acid profiles of pigmented and nonpigmented Aurantiochytrium isolated from Hong Kong mangroves.  J Agric Food Chem 57: 6334-6341.

Fan KW, Vrijmoed LLP, Jones EBG (2002) Physiological studies of subtropical mangrove thraustochytrids.  Bot Mar 45: 50–57

Fan KW, Vrijmoed LLP, Jones EBG (2002) Zoospore chemotaxis of mangrove thraustochytrids from Hong Kong.  Mycologia 94: 569-578  <PDF>

Felsenstein J (1981) Evolutionary trees from DNA sequences: a maximum likelihood approach. J Mol Evol.17: 368-376

Ford SE, Kraeuter JN, Barber RD, Mathis G (2002) Aquaculture associated factors in QPX disease of hard clams: density and seed source.  Aquaculture 208: 23–38.

Frank U, Rabinowitz C. Rinkevich B (1994) In vitro establishment of continuous cell cultures and cell lines from ten colonial cnidarians.  Marine Biology 120: 491-499

Franklin ST, Martin KR, Baer RJ, Schingoethe DJ, Hippen AR (1999) Dietary marine algae (Schizochytrium sp.) increases concentrations of conjugated linoleic, docosahexaenoic and transvaccenic acids in milk of dairy cows. J Nutr 129(11): 2048-2054


Gaertner A. (1966): Vorkommen, Physiologie und Verteilung "Mariner niederer Pilze" (Aquatic Phycomycetes). Veroff. Inst. Meeresforsch. Bremerh., Suppl. 2, 221-236.

Gaertner A. (1967): Niedere mit Pollen koderbare Pilze in dersudlichen Nordsee. Veroff. Inst. Meeresforsch. Bremerh. 10, 159-165.

Gaertner A (1967) Okologische Untersuchungen an einem marinen Pilz aus der Umgebung on Helgoland. Helgolander wiss. Meeresuntersuchungen 15: 181-192

Gaertner A (1968a) Eine methode des quantitativen nechweises nieberer, mit pollen koderbarer pilze im meerwasser und im sediment. Veröff Inst Meeresforsch Bremerh Supple 3: 75-92

Gaertner A (1968b) Die Fluktuationen mariner niederer Pilze in der Deutschen Bucht 1965 und 1966. Veröff Inst Meeresforsch Bremerh Sonderband 3: 105-120

Gaertner A (1968) Niedere, mit Pollen koderbare marine Pilze dies seits und jenseits des Island Faroer Ruckens im Oberflachenwasser und im Sediment.  Veröff Inst Meeresforsch Bremerh 11: 65-82

Gaertner A. (1969) Marine niedere Pilze in Nordsee und Nordatlantik. Ber. Dtsch. Bot. Ges. 82: 287-306.

Gaertner A (1970) Beobachtungen uber die Sporulation der dick-wandigen Sporangien von Thraustochytrium kinnei Gaertner.  Veröff Inst Meeresforsch Bremerh 12: 321-327

Gaertner A (1971) Thraustochytrium kinnei (Thraustochytriaceae) Vegetative Entwicklung.  Encyclopaedia Cinematographica (Editor: G Wolf)

Gaertner A (1972) Sporulation bei Thraustochytiaceae.  Institut fur den Wissenschaftlichen Film

Gaertner A (1972) Characters used in the classification of thraustochytriaceous fungi. Veröff Inst Meeresforsch Bremerh 13: 183-194

Gaertner A (1974) Vorkommen und Verteilung mariner niederer Pilze in der Nordsee und im Nordmeerbecken.  Veröff Inst Meeresforsch Bremerh Suppl 5: 123-147

Gaertner A (1974) Aminoverbindungen, Vitamine und Purinkorper als Nahrstoffkomponenten einiger Thraustochytriaceae.  Veröff Inst Meeresforsch Bremerh Suppl 5: 221-236

Gaertner A (1977) Revision of the Thraustochytriaceae (lower marine fungi) 1. Ulkenia nov. gen. with description of three new species. Veröff Inst Meeresforsch Bremerh 16: 169-157

Gaertner A (1979) Some fungal parasites found in the diatom populations of the Rusfjord area (South Norway) during March 1979. Veroeff. Inst. Meeresforsch. Bremerhav. 18: 29–33.

Gaertner A (1981) A new marine phycomycete, Schizochytrium minutum, sp. nov. (Thraustochytriaceae) from Saline Habitats. Veröff Inst Meeresforsch Bremerh 19: 61-69

Gaertner A (1982) Lower marine fungi from the Northwest African upwelling areas and from the Atlantic off Portugal.  "Meteor" Forschungs-Ergebnisse D 34: 9-30

Gaerther A. and Raghukumar, S. (1980): Ecology of thraustochytrids (lower marine fungi) in the Fladen Ground and other parts of the North sea . I. "Meteor" Forschungsergebnisse A, No. 22: 165-185.

Ganuza E, Anderson AJ, Ratledge C (2008) High-cell-density cultivation of Schizochytrium sp. in an ammonium/pH-auxostat fed-batch system.  Biotechnology Letters 30: 1559-1564  <Link>

Ganuza E, Benítez-Santana T, Atalah E, Vega-Orellana O, Ganga R, Izquierdo MS (2008) Crypthecodinium cohnii and Schizochytrium sp. as potential substitutes to fisheries-derived oils from seabream (Sparus aurata) microdiets.  Aquaculture 277: 109–116  <PDF>

Ganuza E, Izquierdo MS (2007) Lipid accumulation in Schizochytrium G13/2S produced in continuous culture. Appl Microbiol Biotechnol 76(5): 985-990

Gast RJ, Cushman E, Moran DM, Uhlinger KR, Leavitt D, Smolowitz R (2006) DGGE-based detection method for Quahog Parasite Unknown (QPX).  Dis Aquat Org 70: 115–122

Gast RJ, Moran DM, Audemard C, Lyons MM, DeFavari J, Reece KS, Leavitt D, Smolowitz R (2008) Environmental distribution and persistence of Quahog Parasite Unknown (QPX).  Dis. Aquat. Org. 81: 219–229.

Goldstein S (1963) Development and nutrition of new species of Thraustochytrium. Am J Bot 50 (3): 271-279

Goldstein S (1973) Zoosporic marine fungi (Thraustochytriaceae and Dermocystidiaceae). Ann Rev Microbiol 27: 13-26

Grant J, Tekle YI, Anderson OR, Patterson DJ, Katz LA (2009) Multigene evidence for the placement of a heterotrophic amoeboid lineage Leukarachnion sp. among photosynthetic stramenopiles. Protist 160(3): 376-385


Haeckel E (1868) Monographie der moneren. Jena Z Med Naturwiss, medicinisch-naturwissenschaftlichen Gesellschaft, Jena, 4: pp 64-137

Hammond BG, Mayhew DA, Holson JF, Nemec MD, Mast RW, Sander WJ (2001) Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 33(2): 205-217

Hammond BG, Mayhew DA, Kier LD, Mast RW, Sander WJ (2002) Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 35(2): 255-265

Hammond BG, Mayhew DA, Naylor MW, Ruecker FA, Mast RW, Sander WJ (2001) Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 33(2): 192-204

Hammond, BG, Mayhew, DA, Robinson, K, Mast, RW, Sander, WJ. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2001;33(3):356-362

Harel M, Ben-Dov E, Rasoulouniriana D, Siboni N, Kramarsky-Winter E, Loya Y, Barak Z, Wiesman Z, Kushmaro A (2008) A new Thraustochytrid, strain Fng1, isolated from the surface mucus of the hermatypic coral Fungia granulosa. FEMS Microbiol Ecol 64(3): 378-387

Harel M, Koven W, Lein I, Bar Y, Behrens P, Stubblefield J, Zohar Y, Place AR (2002) Advanced DHA, EPA and ArA enrichment materials for marine aquaculture using single cell heterotrophs. Aquaculture 213: 347-362

Harrison, J.L., Jones, E.B.G., 1974. Zoospore discharge in Thraustochytrium striatum. Trans. Br. Mycol. Soc. 62: 283–288.

Harper, J.T., Waanders, E., Keeling, P.J., 2005. On the monophyly of chromalveolates using a six-protein phylogeny of eukaryotes. Int. J. Syst. Evol. Microbiol. 55, 487–496.

Hauvermale A, Kuner J, Rosenzweig B, Guerra D, Diltz S, Metz JG (2006) Fatty acid production in Schizochytrium sp.: involvement of a polyunsaturated fatty acid synthase and a type I fatty acid synthase. Lipids 41:739–747

Hayashi M, Matsumoto R (2001) Ultilization of Thraustochytrid for fishery feed.  Aquabiology 23: 57-61 (in Japanese)

Hayashi M, Matsumoto R, Yoshimatsu T, Tanaka S, Shimizu S (2002) Isolation of highly DHA-accumulated Labyrinthulales and their utilization for nutritional enrichment of rotifers and Artemia.  Nippon Suisan Gakkaishi 68(5): 674-678

Hayashi M, Yukino T, Watanabe F, Miyamoto E, Nakano Y (2007) Effect of vitamin B-12 enriched thraustochytrids on the population growth of rotifers.  Biosci Biotechnol Biochem 71: 221–225

Haydock SF, Aparicio JF, Molnar I, Schwecke T, Khaw LE, Konig A, Marsden AF, Galloway IS, Staunton J, Leadlay PF (1995) Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases.  FEBS Lett 374: 246–248.

Heintzelman MB (2006) Cellular and molecular mechanics of gliding locomotion in eukaryotes. Int Rev Cytol 251: 79-129

Hien HM, Hong ED (2009) Expression of genes encoding for enzyme elongase involved in DHA biosynthesis from Labyrinthula - A heterotrophic marine algae riched in omega-3.  Tap Chi Hoa Hoc 46: 763-771

Hily C, Raffin C, Brun A, den Hartog C (2002) Spatio-temporal variability of wasting disease symptoms in eelgrass meadows of Brittany (France).  Aquatic Botany 72(1): 37-53

Hoehnk W, Ulken A (1979) Pilze aus marinen Schwaemmen. Ver. Institut. Meeresforsch. Bremerh. 17: 99-204

Hofer HW, Pette D, Schwab-Stey H, Schwab D (1972) Enzyme activity pattern and mitochondrio-cytoplasmic relations in protozoa. Comparative study of Tetrahymena pyriformis, Allogromia laticollaris, and Labyrinthula coenocystis. J Protozool 19(3): 532-537

Hohl HR (1966) The fine structure of the slimeways in Labyrinthula. J Protozool 13(1): 41-43  <link>

Hollande A, Enjumet M (1955) Sur l'evolution et la systematique des Labyrinthulidae; Etude de Labyrinthula algeriensis nov. sp.  Annales des sciences naturelles. Sér. 11, Zoologie et biologie
animale  17: 357-368

Honda D (2001) Phylogeny and taxonomy of Labyrinthulids.  Aquabiology 23: 7-18 (in Japanese)

Honda D, Yokochi T, Nakahara T, Erata M, Higaschihara T (1998) Schizochytrium limacinum sp. nov., a new the thraustochytrid from a mangrove area in the west Pacific Ocean.  Mycol Res 102: 439-448

Honda D, Yokochi T, Nakahara T, Raghukumar S, Nakagiri A, Schaumann K, Higashihara T (1999) Molecular phylogeny of labyrinthulids and thraustochytrids based on the sequencing of 18S ribosomal RNA gene.  J Eukaryot Microbiol 46: 637-647

Hori H, Osawa S (1987) Origin and evolution of organisms as deduced from 5S ribosomal RNA sequences.  Mol Biol Evol 4(5): 445-472

Huang H, Bao S (2002) [Studies on production of docosahexaenoic acid by Thraustochytrium aureum] Wei Sheng Wu Xue Bao 42(4): 498-501

Huang H, Bao S (2002) Studies on production of docosahexaenoic acid by Thraustochytrium aureum.  Chinese Journal of Marine Drugs  21: 9-11

Huang J (2005) Isolation of Schizochytrium sp. FJU-512 with high yield of DHA and comparative analysis on its 18S rRNA gene sequence.  Chinese Journal of Applied and Environmental Biology  11: 202-207

Huang J, Aki T, Hachida K, Yokochi T, Kawamoto S, Shigeta S, Ono K, Suzuki O (2001) Profile of Polyunsaturated Fatty Acids Produced by Thraustochytrium sp. KK17-3.  Journal American Oil Chemists Society 78: 605-610

Huang J, Aki T, Kawamoto S, Shigeta S, Ono K, Suzuki O (2002) Enzymatic Preparation of Glycerides Rich in Docosahexaenoic Acid from Thraustochytrid Single Cell Oils by Candida rugosa Lipase.  Journal of Oleo Science 51: 447-456

Huang J, Aki T, Yokochi T, Nakahara T, Honda D, Kawamoto S, Shigeta S, Ono K, Suzuki O (2003) Grouping the newly isolated docosahexanoic fatty acid profile and comparative analysis of 18S rRNA genes.  Mar Biotechnol 5: 450-457

Huang J, Jiang X, Zhang X, Chen W, Tian B, Shu Z, Hu S (2008) Expressed sequence tag analysis of marine fungus Schizochytrium producing docosahexaenoic acid.  J Biotechnol 138(1): 9-16

Huang J, Liu L, Wu S (2005) Profile of Fatty Acids and Analysis of 18S rDNA Sequence in Thraustochytrium sp. FJN10 Highly Produing DHA.  Pharmaceutical Biotechnology (Beijing) 12(1): 1-5

Huiqin H, Shixiang B (2002) Studies on production of docosahexaenoic acid by Thraustochytrium aureum.  Acta Microbiologica Sinica (Chinese edition) 42: 501

Hulsmann N, Galil BS (2001) The effects of freshwater flushing on marine heterotrophic protists--implications for ballast water management. Mar Pollut Bull 42(11): 1082-1086

Hur BK, Cho DW, Kim HJ, Park CI, Suh HJ (2002) Effect of Culture Conditions on Growth and Production of Docosahexaenoic Acid (DHA) using Thraustochytrium aureum ATCC 34304.  Biotechnology and Bioprocess Engineering 7: 10-15

Huth K. (1974): Chytridineen als Parasiten benthischer Algen im Weseraestuar. Veroff. Inst. Meeresforsch. Bremerh. Suppl. 5: 105-113.


Iida I, Nakahara T, Yokochi T, Kamisaka Y, Yagi H, Yamaoka M, Suzuki O (1996) Improvement of docosahexaenoic acid production in a culture of Thraustochytrium aureum by medium optimization. J Ferment Bioeng 81:76–78


Jacobsen K.R. (1983): Thraustochytriaceae im Interstitiun ausgewahlter Sandwatten des Weserastuars. Veroff. Inst. Meeresforsch. Bremerh. 19, 145-175.

Jacobsen AN (2008) Compatible solutes and docosahexaenoic acid accumulation of thraustochytrids of the Aurantiochytrium group.  Doctoral thesis, Norwegian University of Science and Technology. <PDF>

Jain R, Raghukumar S, Sambaiah K, Kumon Y, Nakahara T (2007) Docosahexaenoic acid accumulation in thraustochytrids: search for the rationale.  Marine Biology 151(5): 1657-1664

Jain R, Raghukumar S, Chandramohan D (2004) Enhancement of the production of the polyunsaturated fatty acid, docosahexaenoic acid in thraustochytrid protists. Mar Biotechnol (Suppl) 6:S59–S65

Jain R, Raghukumar S, Tharanathan R, Bhosle NB (2005) Extracellular polysaccharide production by thraustochytrid protists. Mar Biotechnol 7:184–192

Jakobsen AN, Aasen IM, Josefsen KD, Strom AR (2008) Accumulation of docosahexaenoic acid-rich lipid in thraustochytrid Aurantiochytrium sp. strain T66: effects of N and P starvation and O2 limitation. Appl Microbiol Biotechnol 80(2): 297-306

Jakobsen N, Aasen IM, Strom AR (2007) Endogenously synthesized (−)-proto-quercitol and glycine betaine are principal compatible solutes of Schizochytrium sp. strain S8 (ATCC 20889) and three new isolates of phylogenetically related thraustochytrids. Appl Environ Microbiol 73:5848–5856

Jeh EJ, Kumaran RS, Hur BK(2008) Lipid body formation by Thraustochytrium aureum (ATCC 34304) in response to cell age.  Korean Journal of Chemical Engineering 25(5): 1103-1109

Jensen P.R., Jenkins K. M., Porter D. and Fenical W. (1998): Evidence that a new antibiotic flavone glycoside chemically defends the sea grass Tbalassia testudinum against  zoosporic fungi. Appl. Environ. Microbiol. 64, 1490-1496.

Jiang X, Qin L, Tian B, Shu Z, Huang J (2008) [Cloning and expression of two elongase genes involved in the biosynthesis of docosahexaenoic acid in Thraustochytrium sp. FJN-10] Wei Sheng Wu Xue Bao 48(2): 176-183

Jiang X, Qin L, Tian B, Shu Z, Huang J (2008) Biosynthesis of Docosahexaenoic acid in Thraustochytrium sp. FJN-10.  Acta Microbiologica Sinica (Chinese edition) 48(2): 183-189

Jiang Y, Fan K-W, Wong RT-Y, Chen F (2004) Fatty acid composition and squalene content of the marine microalga Schizochytrium mangrovei. J Agric Food Chem 52:1196–1200

Johnson TW, Sparrow FK (1961) Fungi in oceans and estuaries. J Cramer, Weinheim. pp 330-333

Jones EBG, Alderman DJ (1971) Althornia crouchii gen. et sp. nov. A marine biflagellate fungus. Nova Hedwigia 21: 381-399

Jones E.B.G. and Alias S.A. (1997): Biodiversity of mangrove fungi. ln: Hyde K.D. (ed.): Biodiversity of Tropical Microfungi. Hong Kong University Press, Hong Kong.

Jones E.B.G. and Harrison J.L. (1976):Physiology of marine Phycomycetes. In: Jones E.BG. (ed.): Recent Advances in Aquatic Mycology. pp. 261-278. Elek Science, London.

Jones G.M. and O'Dor R.K. (1983): Ultrastructural observations on a thraustochytrid fungus parasitic in the gills of squid (Ilex illecebrosus LeSueur). J.Parasitol. 69, 903-911.


Kang D, Anbu P, Kim WH, Hur BK (2008) Coexpression of Elo-like enzyme and 5, 4-desaturases derived from Thraustochytrium aureum ATCC 34304 and the production of DHA and DPA in Pichia pastoris.  Biotechnology and Bioprocess Engineering 13(4): 483-490

Kang DH, Jeh EJ, Seo JW, Chun BH, Hur BK (2007) Effect of salt concentration on production of polyunsaturated fatty acids in Thraustochytrium aureum ATCC 34304.  Korean Journal of Chemical Engineering 24(4): 651-654

Karling JS (1981) Predominantly holocarpic and eucarpicsimple biflagellate Phycomycetes. J Cramer, Vaduz

Kazama F (1972a) Ultrastructure of Thraustochytrium sp. zoospores. I. Kinetosome. Arch Mikrobiol 83(3): 179-188

Kazama FY (1972b) Ultrastructure of Thraustochytrium sp. zoospores. II. Striated inclusions. J Ultrastruct Res 41(1): 60-66

Kazama FY (1974) Ultrastructure of Thraustochytrium sp. zoospores. IV. External morphology with notes on the zoospores of Schizochytrium sp. Mycologia 66: 272-280

Kazama FY (1975) Cytoplasmic cleavage during zoosporogenesis in Thraustochytrium sp.: ultrastructure and the effects of colchicine and D2O. J Cell Sci 17(1): 155-170

Kazama FY, Schornstein KL (1972) Herpes-type virus particles associated with a fungus. Science 177: 696–697.

Kazama FY, Schornstein KL (1973) Ultra-structure of a fungus herpes-type virus. Virology 52: 478–487.

Kazama FY, Zachary AL, Schornstein KL (1975) Observation on Thraustochytrium sp.: development and behavior in culture. Can J Bot 53: 360-374

Kegang W, Xianghua C, Liansheng Y (2003) Effects of Phytohormones on Growth and DHA Production by Thraustochytrium roseum.  Acta Microbiologica Sinica (Chinese edition) 43: 111-115

Kendrick A, Ratledge C (1992) Lipids of selected molds grown for production of n-3 and n-6 polyunsaturated fatty acids. Lipids 27: 15–20

Kimura H, Fukuba T, Naganuma T (1999) Biomass of thraustochytrid protoctists in coastal water. Mar Ecol Prog Ser 189: 27–33

Kimura H, Naganuma T(2001) Ecological roles of thraustochytrids in coastal waters.  Aquabiology 23: 19-25 (in Japanese)

Kimura H, Sato M, Sugiyama C, Naganuma T (2001) Coupling of thraustochytrids and POM, and of bacterio- and phytoplankton in a semi-enclosed coastal area: implication for different substrate preference by the planktonic decomposers.  Aquatic Microbial Ecology 25: 293-300

Kiy T, Rusing M, Fabritius D (2005) Producion of docosahexaenoic acid by the marine Microalga, Ulkenia sp. in: Cohen Z, Ratledge C (Eds.), Single Cell Oils AOCS Press, pp. 99–106.

Kleinschuster SJ, Smolowitz R, Parent J (1998) In vitro life cycle and propagation of Quahog Parasite Unknown.  J. Shellfish Res. 17:75–78.

Klie H, Mach F (1968) [Light and electron microscopic studies of the effect of Labyrinthula enzyme on bacterial and yeast cells] Z Allg Mikrobiol 8(5): 385-395

Klie H, Schwartz W (1969) [Nutrition physiology of Labyrinthula coenocystis Schmoller] Z Allg Mikrobiol 9(1): 17-30

Kobayashi Y, Ookubo M (1953) Studies on the marine Phycomycetes. Bull Natio Sci Mus Tokyo 33: 53-65

Konno, K. (1969): Studies on the Japanese lower aquatic phycomycetes II, on Thraustochytrium collected from a seaweed. Trans. Mycol. Soc. Japan 10, 9-13.

Kreger-van Rij (1984) The yeasts, a taxonomic study. North-Holland, Amsterdam

Kumon Y, Kamisaka Y, Tomita N, Kimura K, Uemura H, Yokochi T, Yokoyama R, Honda D. (2008) Isolation and characterization of a Delta5-desaturase from Oblongichytrium sp. Biosci Biotechnol Biochem 72(8): 2224-2227

Kumon Y, Yokochi T, Nakahara T, Yamaoka M, Mito K (2002) Production of long-chain polyunsaturated fatty acids by monoxenic growth of labyrinthulids on oil-dispersed agar medium. Appl Microbiol Biotechnol 60:275–280

Kumon Y, Yokochi T, Nakahara T (2005b) High yields of long-chain polyunsaturated fatty acids by labyrinthulids on soybean lecithin dispersed agar medium.  Appl Microbiol Biotechnol 69: 253–258

Kumon Y, Yokoyama R, Yokochi T, Honda D, Nakahara T (2003) A new labyrinthulid isolate, which solely produces n-6 docosapentaenoic acid. Appl Microbiol Biotechnol 63: 22-28

Kumon Y, Yokoyama R, Haque Z,Yokochi T, Honda D, Nakahara T (2006) A new labyrinthulid isolate that produces only docosahexaenoic acid. Mar Biotechnol 8: 170-177

Kurtzman CP, Fell JW (1996) The yeasts, a taxonomic study. North-Holland, Amsterdam

Kvingedal R, Owens L, Jerry DR (2006) A new parasite that infects eggs of the mud crab, Scylla serrata, in Australia. J Invertebr Pathol 93(1): 54-59


Lali SC, Yokochi T, Nakahara T (2001) Conversion of 18-carbon Fatty Acids to Long Chain Polyunsaturated Fatty Acids in Some Thraustochytrids.  Journal of Oleo Science 50: 515-520

Le PM, Fraser C, Gardner G, Liang WW, Kralovec JA, Cunnane SC, Windust AJ (2007) Biosynthetic production of universally (13)C-labelled polyunsaturated fatty acids as reference materials for natural health product research. Anal Bioanal Chem 389(1): 241-249

Leander CA, Porter D (2000) Redefining the genus Aplanochytrium (phylum Labyrinthulomycota). Mycotaxon 76: 439-444

Leander CA, Porter D (2001) The Labyrinthulomycota is comprised of three distinct lineages. Mycologia 93: 459-464

Leander CA, Porter D, Leander BS (2004) Comparative morphology and molecular phylogeny of aplanochytrids (Labyrinthulomycota). Eur J Protistol 40: 317-328  <PDF>

Le-Campion-Alsumard T., Golubic S. and Priess K. (1995): Fungi in corals: Symbiosis or disease? Interaction between poiyps and fungi causes pearl-like skeleton biomineralization. Mar. Ecol. Prog. Ser. 117, 137-147.

Leipe DD, Wainright PO, Gunderson JH, Porter D, Patterson DJ, Valois F, Himmerich S, Sogin ML (1994) The stramenopiles from a molecular perspective: 16S-like rRNA sequences from Labyrinthuloides minuta and Cafeteria roenbergensis. Phycologia 33: 369-377

Levine ND, Corliss JO (1963) Two new subclasses of sarcodines, LABYRINTHULIA subcl. nov. and PROTEOMYXIDIA subcl. nov. J Protozool 10(Suppl.): 27

Levine ND, Corliss JO, Cox FEG, Deroux G, Grain J, Honigberg BM, Leedale GF, Loeblich AR, Lom J, Lynn DH, Merinfeld D, Page FC, Poljansky G, Sprague V, Vavra J, Wallace FG (1980) A newly revised classification of the Protozoa.  J Protozool 27: 37-58

Lewis TE, Mooney BD, McMeekin TA, Nichols PD (1998) New Australian microbial sources of polyunsaturated fatty acids.  Chem Aust 65:37–39

Lewis TE, Nichols PD, Mcmeekin TA (1999) The Biotechnological potential of thraustochytrids. Mar Biotechnol 1: 580-587

Lewis TE, Nichols PD, Mcmeekin TA (2001) Sterol and Squalene Content of a Docosahexaenoic-Acid-Producing Thraustochytrid: Influence of Culture Age, Temperature, and Dissolved Oxygen.  Marine Biotechnology3(5): 439-447

Li MH, Robinson EH, Tucker CS, Manning BB, Khoo L (2009) Effects of dried algae Schizochytrium sp., a rich source of docosahexaenoic acid, on growth, fatty acid composition, and sensory quality of channel catfish Ictalurus punctatus.  Aquaculture 292(3-4): 232-236

Li Q, Chen GQ, Fan KW, Lu FP, Aki T, Jiang Y (2009) Screening and Characterization of Squalene-Producing Thraustochytrids from Hong Kong Mangroves. J Agric Food Chem 57(10): 4267-4272

Li ZP, Jiang XZ, Tian BY, Shu ZY, Huang JZ (2008) Cloning and Expression of Acyl Carrier Protein Gene from Schizochytrium.  Microbiology (Beijing) 35(2): 256-260

Li ZY, Ward OP (1994) Production of docosahexaenoic acid (DHA) by Thraustocytrium roseum. J Ind Microbiol 13:238–341

Lippmeier JC, Crawford KS, Owen CB, Rivas AA, Metz JG, Apt KE (2009) Characterization of both polyunsaturated fatty acid biosynthetic pathways in Schizochytrium sp. Lipids 44(7): 621-630

Liu Q, Allam B, Collier JL (2009) Quantitative real-time PCR assay for QPX (Thraustochytriidae), a parasite of the hard clam (Mercenaria mercenaria). Appl Environ Microbiol 75(14): 4913-4918

Loganathan B, Venugopaian VK, Raghukumar S (1985): Schizochytrium sp. associated with external lesions of some estuarine fishes. J. Singapore Natl. Acad. Sci. 14, 132-134.

Lu HT, Jiang Y, Chen F (2003) Preparative separation and purification of squalene from the microalga Thraustochytrium ATCC 26185 by high-speed counter-current chromatography. J Chromatogr A 994(1): 37-43

Luo Q, Krumholz LR, Najar FZ, Peacock AD, Roe BA, White DC, Elshahed MS (2005) Diversity of the microeukaryotic community in sulfide-rich Zodletone Spring (Oklahoma). Appl Environ Microbiol 71(10): 6175-6184

Lyons MM, Smolowitz R, Dungan CF, Roberts SB (2006) Development of a real time quantitative PCR assay for the hard clam pathogen Quahog Parasite Unknown (QPX).  Dis Aquat Org 72: 45–52.

Lyons MM, Ward JE, Smolowitz R, Uhlinger KR, Gast RJ (2005) Lethal marine snow: pathogen of bivalve mollusc concealed in marine aggregates.  Limnol Oceanogr 50: 1983–1988. <PDF>


MacKay RM, Doolittle WF (1982) Two thraustochytrid 5S ribosomal RNAs. Nucleic Acids Res 10(24): 8307-8310

MacCallum GS, McGladdery SE (2000) Quahog Parasite Unknown (QPX) in the northern quahog Mercenaria mercenaria (Linnaeus, 1758) and M. mercenaria var. notata from Atlantic Canada, survey results from three maritime provinces.  J Shellfish Res 19: 43–50.

Mann K,H. (1988): Production and use of detritus in various freshwater, estuarine and coastal marine ecosystems.  Limnol Oceanogr 33: 910-930.

Margulis L, Olendzenski L, Dolan M, MacIntyre F (1996) Diversity of eukaryotic microorganisms: computer-based resources, "The Handbook of Protoctista" and its "Glossary". Microbiologia 12(1): 29-42

Martin DL, Boone E, Caldwell MM, Major KM, Boettcher AA (2009) Liquid culture and growth quantification of the seagrass pathogen, Labyrinthula spp. Mycologia 101(5): 632-635

Massana R, Castresana J, Balague V, Guillou L, Khadidja R, Groisillier A, Valentin K, Pedros-Alio C (2004) Phylogenetic and ecological analysis of novel marine stramenopiles.  Applied and Environmental Microbiology 70: 3528-3534. <PDF>

McKone KL, Tanner CE (2009) Role of salinity in the susceptibility of eelgrass Zostera marina to the wasting disease pathogen Labyrinthula zosterae.  Marine Ecology Progress Series 377: 123-130

McLean I.N. and Porter D. (1987): Lesions produced by a thraustochytrid in Tritonia diomedea (Mollusca: Gastropoda: Nudibranchia). J. Invert. Pathol. 49,223-225.

Metz JG, Kuner J, Rosenzweig B, Lippmeier JC, Roessler P, Zirkle R (2009) Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. Plant Physiol Biochem 47(6): 472-478

Metz JG, Roessler P, Facciotti D, Levering C, Dittrich F, Lassner M, Valentine R, Lardizabal K, Domergue F, Yamada A, Yazawa K, Knauf V, Browse J (2001) Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes.  Science 293: 290–293.

Meyer A, Cirpus P, Ott C, Schlecker R, Zahringer U, Heinz E (2003) Biosynthesis of docosahexaenoic acid in Euglena gracilis: biochemical and molecular evidence for the involvement of a Delta4-fatty acyl group desaturase.  Biochemistry 42(32): 9779-9788

Michaud AL, Diau GY, Abril R, Brenna JT (2002) Double bond localization in minor homoallylic fatty acid methyl esters using acetonitrile chemical ionization tandem mass spectrometry.  Anal Biochem 307(2): 348-360

Miller J.D. and Whitney N.J. (1981):Fungi of the Bay of Fundy IV: Thraustochytrids. Nova Hedwigia 35, 407-416.

Miller MR, Nichols PD, Carter CG (2007) Replacement of fish oil with thraustochytrid Schizochytrium sp. L oil in Atlantic salmon parr (Salmo salar L) diets. Comp Biochem Physiol A Mol Integr Physiol 148(2): 382-392

Miyamoto E, Tanioka Y, Yukino T, Hayashi M, Watanabe F, Nakano Y (2007) Occurrence of 5'-deoxyadenosylcobalamin and its physiological function as the coenzyme of methylmalonyl-CoA mutase in a marine eukaryotic microorganism, Schizochytrium limacinum SR21. J Nutr Sci Vitaminol (Tokyo) 53(6): 471-475

Mo C, Douek J, Rinkevich B (2002) Development of a PCR strategy for thraustochytrid identification based on 18S rDNA sequence. Mar Biol 140: 883-889

Mo C, Rinkevich B (2001) A simple, reliable, and fast protocol for thraustochytrid DNA extraction. Mar Biotechnol (NY) 3(2): 100-102

Moens PB, Perkins FO (1969) Chromosome number of a small protist: accurate determination. Science 166(910): 1289-1291

Morita E, Kumon Y, Nakahara T, Kagiwada S, Noguchi T (2006) Docosahexaenoic acid production and lipid-body formation in Schizochytrium limacinum SR21. Mar Biotechnol 8: 319–327

Moro I, Negrisolo E, Callegaro A, Andreoli C (2003) Aplanochytrium stocchinoi a new Labyrinthulomycota from the Southern Ocean (Ross Sea, Antarctica). Protist 154: 331-340

Moss ST (1980) Ultrastructure of the endomembrane-sagenogenetosome-ectoplasmic net complex in Ulkenia visurgensis (Thraustocytriales).  Botanica Marina 23: 73-94

Moss ST (1985) An ultrastructural study of taxonomically significant characters of the Thraustochytriales and the Labyrinthulales.  J Linn Soc (Bot) 91: 329-357

Moss, T.S., 1991. Thraustochytrids and other zoosporic marine fungi.  In: Patterson DJ, Larsen J (Eds) The Biology of Free-Living Heterotphic Flagellates.  Systematics Association Special, vol. 45. Clarendon Press, Oxford, pp. 415–425.

Muehlstein LK, Porter D. Short FT (1988) Labyrinthula sp., a marine slime mold producing the symptoms of wasting disease in eelgrass, Zostera marina.  Mar Biol 99: 465-472

Muehlstein LK, Porter D, Short FT (1991) Labyrinthula zosterae sp. nov., the causative agent of wasting disease of eelgrass, Zostera marina.  Mycologia 83: 180-191  <Link>


Nagano N, Taoka Y, Honda D, Hayashi M (2009) Optimization of culture conditions for growth and docosahexaenoic acid production by a marine thraustochytrid, Aurantiochytrium limacinum mh0186.  Journal of Oleo Science 58: 623-628. <PDF>

Naganuma T, Kimura H, Karimoto R, Pimenov NV (2006) Abundance of planktonic thraustochytrids and bacteria and the concentration of particulate ATP in the Greenland and Norwegian Seas.  Polar Bioscience 20: 37-45

Naganuma T, Takasugi H, Kimura H (1998) Abundance of thraustochytrids in coastal plankton. Mar Ecol Prog Ser 162: 105–110 <PDF>

Nakagiri A (2001) Ecology of Labyrinthula and note on modified methods for cultivation and preservation of the isolates.  Aquabiology 23: 32-38 (in Japanese)

Nakahara T, Yokochi T, Higashihara T, Tanaka S, Yaguchi T, Honda D (1996) Production of docosahexaenoic and docosapentaenoic acid by Schizochytrium sp. iolated from Yap Island.  J Am Oil Chem Soc 73: 1421-1426

Nakatsuji N, Nakatsuji T, Bell E (1981) Formation of whirling aggregates by Labyrinthula vegetative cells. Exp Cell Res 131(2): 412-417

Nakayama T., Watanabe S., Mitsui K., Uchida H., Inouye I. (1996) The phylogenetic relationship between the Chlamydomonadales and Chlorococcales inferred from 18S rDNA sequence data. Phycol Res 44 :


Olive LS (1975) The Mycetozoans. Academic, New York. pp 215-292

Olsen MW (2007) Labyrinthula terrestris: a new pathogen of cool-season turfgrasses.  Molecular Plant Pathology 8(6): 817-820

Olsen MW, Bigelow DM, Gilbertson RL, Stowell LJ, Gelernter WD (2003) First Report of a Labyrinthula sp. Causing Rapid Blight Disease of Rough Bluegrass and Perennial Ryegrass.  Plant Disease 87: 1267

Okuyama H, Orikasa Y, Nishida T (2007) In vivo conversion of triacylglycerol to docosahexaenoic acid-containing phospholipids in a thraustochytrid-like microorganism, strain 12B.  Biotechnol Lett 29: 1977–1981


Park HG, Puvanendran V, Kellett A, Parrish CC, Brown JA (2006) Effect of enriched rotifers on growth, survival, and composition of larval Atlantic cod (Gadus morhua).  ICES Journal of Marine Science 63(2): 285-295

Patil V, Brate J, Shalchian-Tabrizi K, Jakobsen KS (2009) Revisiting the phylogenetic position of Synchroma grande.  J Eukaryot Microbiol 56(4): 394-396

Patterson DJ (1989) Stramenopiles, chromophytes from a protistan perspectives.  In: Green JC, Leadbeater BSC, Diver WL (Eds) The Chromaphyte Algae Problems and Perspectives. Clarendon Press, Oxford, pp. 357–379.

Perkins FO (1970) Formation of centriole and centriole-like structures during meiosis and mitosis in Labyrinthula sp. (Rhizopodea, Labyrinthulida). An electron-microscope study.  J Cell Sci 6(3): 629-653

Perkins FO (1972) The ultrastructure of hold-fasts, "rhizoids" and "slime track" in traustochytriaceous fungi and in Labyrinthula spp.  Arch Microbiol 84: 95-118

Perkins FO (1973) A new species of marine labyrinthulid Labyrinthuloides yorkensis gen. nov. spec. nov. – cytology and fine structure.  Arch Microbiol 90: 1-17

Perkins FO (1974) Phylogenetic consideration of the problematic thraustochytriaceous – labyrinthulid - Dermocystidium complex based on observation of fine structure.  Veröff Inst Meeresforsch Bremerh 5: 45-63

Perkins FO (1974) Reassignment of Labyrinthula minuta to the genus Labyrinthuloides. Mycologia 66: 697–702

Perkins FO, Amon JP (1969) Zoosporulation in Labyrinthula sp.: an electron microscopic study. J Protozool 16: 235–257.

Perveen Z, Ando H, Ueno A, Ito Y, Yamamoto Y, Yamada Y, Takagi T, Kaneko T, Kogame K, Okuyama H (2006) Isolation and characterization of a novel thraustochytrid-like microorganism that efficiently produces docosahexaenoic acid.  Biotechnol Lett 28: 197–202

Phleger CF, Nelson MM, Mooney BD, Nichols PD (2001) Interannual variations in the lipids of the Antarctic pteropods Clione limacina and Clio pyramidata.  Comp Biochem Physiol B Biochem Mol Biol 128(3): 553-564

Pokorny KS (1967) Labyrinthula. J Protozool 14: 697-708

Polglase JL (1980) A preliminary report on the thraustochytrid(s) and labyrinthurid(s) associated with a pathological condition in lesser octopus Eledone cirrhosa. Bot Mar 23:699–706

Pond DW, Bell MV, Harris RP, Sargent JR (1998) Microplanktonic polyunsaturated fatty acid markers: a mesocosm trial. Est.  Coast Shelf Sci 46: 61-67

Porter D (1969) Ultrastructure of Labyrinthula.  Protoplasma 67: 1–19

Porter D (1972) Cell division in the marine slime mold, Labyrinthula sp. and the role of the bothrosome in extracellular membrane production.  Protoplasma 74: 427-448

Porter D (1974) Phylogenetic considerations of the Thraustochytriaceae and Labyrinthulaceae. Veröffentlichungen des Instituts fuer Meeresforschung in Bremerhaven. Sonderband 5: 19-44

Porter D (1990) Phylum Labyrinthulomycota. In Margulis L, Corlis JO, Melconian M, Chapman DJ (Eds) Handbook of Protoctista, Jones and Barlett, Boston, pp 388-398

Preston TM, King CA (2005) Actin-based motility in the net slime mould Labyrinthula: evidence for the role of myosin in gliding movement.  J Eukaryot Microbiol 52(6): 461-475

Pyle DJ, Garcia RA, Wen Z (2008) Producing docosahexaenoic acid (DHA)-rich algae from biodiesel-derived crude glycerol: effects of impurities on DHA production and algal biomass composition. J Agric Food Chem 56(11): 3933-3939


Qian H, Liu Q, Allam B, Collier JL (2007) Molecular genetic variation within and among isolates of QPX (Thraustochytridae), a parasite of the hard clam Mercenaria mercenaria.  Dis Aquat Org 77: 159–168.

Qiu X, Hong H, MacKenzie SL (2001) Identification of a Delta4 fatty acid desaturase from Thraustocytrium sp. involved in the biosynthesis of docosahexaqenoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea.  J Biol Chem 276: 31561–31566

Quick JA (1974a) A new marine Labyrinthula with unusual locomotion. Trans. Am. Microsc. Soc. 93: 52-61.

Quick JA (1974b) Labyrinthuloides schizochytrops n. sp., a new marine labyrinthula with spheroid "spindle"
cells.  Trans. Am. Microsc. Soc. 93, 344–365.


Rabinowitz C, Douek J, Weisz R, Shabtay A, Rinkevich B (2006) Isolation and characterization of four novel thraustochytrid strains from a colonial tunicate.  Indian J Mar Sci 35: 341-350

Ragan MA, MacCallum GS, Murphy CA, Cannone JJ, Gutell RR, McGladdery SE (2000) Protistan parasite QPX of hardshell clam Mercenaria mercenaria is a member of Labyrinthulomycota.  Dis Aquat Org 42: 185–190

Raghukumar C (1986) Thraustochytrid fungi associated with marine algae.  Indian J Mar Sci 15: 121-122

Raghukumar C (1987b) Fungal parasites of the marine green algae, Cladophora and and Rhizoclnium.  Bot Mar 29: 289-297

Raghukumar C and Raghukumar S (1992) Association of thraustochytrids and fungi with living marine algae.  Mycol Res 96: 542-546

Raghukumar C, Raghukumar S, Sharma S, Chandramohan D (1992) Endolithic fungi from deep-sea calcareous sudstrata. Isolation and laboratory studies.  In: Desai BN (Ed) Ocean.  Oxford & IBH, New Delhi. pp. 3-9.

Raghukumar S (1977) A new species of the genus Ulkenia Gaertner (lower marine fungi) from the North Sea.  Veröff Inst Meeresforsch Bremerh 16: 159-165

Raghukumar S (1982a) Fine structure of the thraustochytrid Ulkenia amoeboidea. I. Vegetative thallus and formation of the amoeboid stage.  Can J Bot 60: 1092-1102

Raghukumar S (1982b) Fine structure of the thraustochytrid Ulkenia amoeboidea. II. The amoeboid stage and formation of zoospores.  Can J Bot 60: 1103-1114

Raghukumar S (1985) Enumeration of thraustochytrids (heterotrophic microorganisms) from theArabian Sea.  Mahasagar, Bull. Natl. Oceanogr. 18, 457-465.

Raghukumar S (1987) A device for continuous observation of microscopic aquatic organisms. Indian J Mar Sci 30: 83-89

RaghuKumar S (1987) Occurrence of the thraustochytrid, Corallochytrium limacisporum gen. et sp. nov. in the coral reef lagoons of the Lakshadweep Islands in the Arabian Sea.  Botanica Marina 30(1): 83-89

Raghukumar S (1988) Schizochytrium mangrovei sp. nov., a thraustochytrid from mangroves in India. Trans Br Mycol Soc 90: 627-631

Raghukumar S (1988) Detection of the thraustochytrid protist Ulkenia visurgensis in a hydroid, using immunofluoescence.  Mar Biol 97: 253-258

Raghukumar S (1988) Schizochytrium octosporum sp. nov. and other thraustochytrids from the North Sea (Rosfjord, Norway).  Trans Br Mycol Soc 90: 273-278

Raghukumar S (1992) Bacterivory: a novel dual role for thraustochytrids in the sea.  Marine Biology 113: 165-169  <PDF>

Raghukumar S (1996) Morphology, taxonomy, and ecology of thraustochytrids and labyrinthulids, the marine counterparts of zoosporic fungi.  In: Dayal R (Ed) Advances in zoosporic fungi. Publications Pvt. Ltd., New Delhi, pp. 35–60

Raghukumar S (2002) Ecology of the marine protists, the Labyrinthulomycetes (thraustochytrids and labyrinthulids).  Eur J Protistol 38: 127–145 <Link>

Raghukumar S (2006) Marine eukaryote diversity, with particular reference to fungi: lessons learnt from prokaryotes.  Indian J Mar Sci 35: 388-398

Raghukumar S (2008) Thraustochytrid Marine Protists: Production of PUFAs and Other Emerging Technologies.  Marine Biotechnology 10(6): 631-640

Raghukumar S, Anil AC, Khandeparkar L, Patil JS (2000) Thraustochytrid protists as a component of marine microbial films. Mar. Biol. 136: 603–609.  <PDF>

Raghukumar S, Raghukumar C (1988) A report on the occurrence of thraustochytrid species in Indian waters.  Kavaka 16: 40-44

Raghukumar S, Ramaiah N, Raghukumar C (2001) Dynamics of thraustochytrid protists in the water column of the Arabian Sea.  Aquat Microb Ecol 24: 175–186

Raghukumar S, Schaumann K (1993) An epifluorescence microscopy method for direct detection and enumeration of the fungi-like marine protists, the thraustochytrids. Limnol Oceanogr 38: 182–187.

Raghukumar S, Sharma S, Raghukumar C, Sathe-Pathak V (1994) Thraustochytrid and fungal component of marine detritus. IV. Laboratory studies on decomposition of leaves of the mangrove Rhizophora apiculata Blume.  J Exp Mar Biol Ecol 183: 113–131

Ragone Calvo LM, Walker JG, Burreson EM (1998) Prevalence and distribution of QPX, Quahog Parasite Unknown, in hard clams, Mercenaria mercenaria in Virginia, USA.  Dis Aquat Org 33: 209–219  <Link>

Raikar MT, Raghukumar S, Vani V, David JJ, Chandramohan D (2001) Thraustochytrid protists degrade hydrocarbons.  Indian J Mar Sci 30: 139–145

Ralph PJ, Short FT (2002) Impact of the wasting disease pathogen, Labyrinthula zosterae, on the photobiology of eelgrass Zostera marina.  Marine Ecology Progress Series 226: 265-271

Ramaiah N, Raghukumar S, Gauns M (1996) Bacterial abundanse and production in the central and eastern Arebian Sea.  Curr Sci 71: 878-882

Ramaiah N, Raghukumar S, Mangesh G, Madhupratap M (2005) Seasonal variations in carbon biomass of bacteria, thraustochytrids and microzooplankton in the Northern Arabian Sea.  Deep Sea Research part 2 52(14-15): 1910-1921

Ratledge C (2004) Fatty acid biosynthesis in microorganisms being used for single cell oil production. Biochimie 11:807–815

Ren LJ, Huang H, Xiao AH, Lian M, Jin LJ, Ji XJ (2009) Enhanced docosahexaenoic acid production by reinforcing acetyl-CoA and NADPH supply in Schizochytrium sp. HX-308. Bioprocess Biosyst Eng 32(6): 837-843

Renn CE (1942) Demonstration of Labyrinthula parasite in eel-grass from the coast of California.  Science 95(2457): 122

Reynolds ES (1963) The use of lead citrate at high pH as an electronopaque strain in electron microscopy.  J Cell Biol 17: 208-212

Riemann F, Schaumann K (1993) Tharaustochytrid protists in Antarctic fast ice?  Antarct Sci 5: 279-280

Riisberg I, Orr RJ, Kluge R, Shalchian-Tabrizi K, Bowers HA, Patil V, Edvardsen B, Jakobsen KS (2009) Seven gene phylogeny of heterokonts. Protist 160(2): 191-204

Rinkevich B (1999) Cell cultures from marine invertebrates: obstacles, new approaches and recent improvements. Journal of Biotechnology 70: 133-153

Ritar AJ, Dunstan GA, Nelson MM, Brown MR, Nichols PD, Thomas CW, Smith EG, Crear BJ, Kolkovski S (2004) Nutritional and bacterial profiles of juvenile Artemia fed different enrichments and during starvation.  Aquaculture 239: 351-373

Robin JH, Vincent B (2003) Microparticulate diets as first food for gilthead sea bream larva (Sparus aurata): study of fatty acid incorporation.  Aquaculture 225: 463-474

Rosa SM, Galvagno MA, Vélez CG (2006) Primeros aislamientos de Thraustochytriales (Labyrinthulomycetes, Heterokonta) de ambientes estuariales y salinos de la Argentina. (= First isolations of Thraustochytriales (Labyrinthulomycetes, Heterokonta) from estuarial and saline environments of Argentina).  Darwiniana 44: 81-88.  <PDF>

Rzhetsky A, Nei M (1992) A simple method for estimating and testing minimum-evolution trees. Mol Biol Evol 9: 945-967

Rzhetsky A, Nei M (1993) Theoretical foundation of the minimum-evolution method of phylogenetic inference. Mol Biol Evol 10: 1073-1095


Sakata T, Fujisawa T (1996) Isolation of algophorous Labyrinthula and amoebae from marine habitats.  Mem Fac Fish Kagoshima Univ  45: 13-19  <PDF>

Sakata T, Fujisawa T, Yoshikawa T (2000) Colony formation and fatty acid composition of marine labyrinthulid isolates grown on agar plates.  Fish Sci 66: 84–90

Sakata T, Iwamoto K (1995) Isolation of marine algicidal microorganisms on diatom double layer agar plates.  Fish Sci 61: 173–174

Sakata T, Yoshikawa T (2001) Algicidal activity and nutrition of labyrinthulids.  Aquabiology 23: 26-31 (in Japanese)

Sanders TA, Gleason K, Griffin B, Miller GJ (2006) Influence of an algal triacylglycerol containing docosahexaenoic acid (22 : 6n-3) and docosapentaenoic acid (22 : 5n-6) on cardiovascular risk factors in healthy men and women.  Br J Nutr 95(3): 525-531

Santangelo G, Bongiorni L, Pignataro L (2000) Abundance of thraustochytrids and ciliated protozoans in a Mediterranean sandy shore determined by an improved, direct method.  Aquatic Microbial Ecology 23: 55-61  <Link>

Sargent JR, Bell MV, Henderson RJ (1995) Protists as sources of (n-3) polyunsaturated fatty acids for verterate development.  In: Brugerolle G, Mignot J-P (Eds) Proceedings of the Second European Congress of Protistology. Clermont-Ferrand, pp 55–64

Sathe V, Raghukumar S (1991) Fungi and their biomass in detritus of the seagrass Thalassia hemprichii (Ehrenberg) Ascherson.  Botanica Marina 34: 271-277.

Sathe-Pathak V, Raghukumar S, Raghukumar C, Sharma S (1993) Thraustochytrid and fungal component of marine detritus. I - Field studies on decomposition of the brown alga Sargassum cinereum J. Ag.  Indian Journal of Marine Sciences 22: 159-167.

Scharer L, Knoflach D, Vizoso DB, Rieger G, Peintner U (2007) Thraustochytrids as novel parasitic protists of marine free-living flatworms: Thraustochytrium caudivorum sp. nov. parasitizes Macrostomum lignano. Marine Biology 152: 1095-1104.  <PDF>

Schmoller H (1960) [The culture and development of Labyrinthula coenocystis n. sp.]  Arch Mikrobiol 36: 365-372

Schmoller H (1961) [On the development of Labyrinthula.] Arch Mikrobiol 40: 224-230

Schmoller H (1966) [Nature of the labyrinthules] Naturwissenschaften 53(24): 711-712

Schmoller H (1967) Die Bewegung der Labyrinthulen. [Movement of the Labyrinthulae.] Naturwissenschaften 54(13): 345

Schmoller H, Wiegershausen B (1968) Die Labyrinthulen als Pilzparasiten. [Labyrinthulae as fungal parasites.] Naturwissenschaften 55(12): 657-658

Schmoller H, Wiegershausen B (1969) Weitere Untersuchungen uber den Parasitismus von Labyrinthula gegenuber Pilzen. [Further studies on the parasitism of fungi by Labyrinthulae.] Experientia 25(6): 661-662

Schneider J (1969) Uber niedere Pilze der westlichen Ostsee.  Ber Dtsch Bot Ges 81: 375-379

Scholz E (1958) Uber morphologische Modifikationen bei niederen Erdphycomyceten and Beschreibung zweier neuer Arten von Rhizophydium und Thraustochytrium.  Arch. Mikrobiol. 29: 354-362

Schwab-Stey H, Schwab D (1974) Hypothetical origin of the particular membrane relationships in Labyrinthula.  Protoplasma 81(1): 125-130

Shabala L, McMeekin T, Shabala S (2009) Osmotic adjustment and requirement for sodium in marine protist thraustochytrid.  Environmental Microbiology 11(7): 1835-1843

Shabala L, Shabala S, Ross T, McMeekin T (2001) Membrane transport activity and ultradian ion flux oscillations associated with cell cycle of Thraustochytrium sp.  Australian Journal of Plant Physiology 28: 87-99

Shields RJ, Bell JG, Luizi FS, Gara B, Bromage NR, Sargent JR (1999) Natural copepods are superior to enriched Artemia nauplii as feed for halibut larvae (Hippoglossus hippoglossus) in terms of survival, pigmentation and retinal morphology: relation to dietary essential fatty acids. J Nutr 129(6): 1186-1194  <Link>

Shimizu S, Kawashima H, Shinmen Y, Akimoto K, Yamada H (1988) Production of eicosapentaenoic acid by Mortierella fungi.  J Am Oil Chem Soc 65: 1455-1459

Shirasaka N (2001) Approaches to modification of fatty acid composition of Schizochytrium limacinum SR21.  Aquabiology 23: 52-56

Shirasaka N, Hirai Y, Nakabayashi H, Yoshizumi H (2005) Effect of cyanocobalamin and p-toluic acid on the fatty acid composition of Schizochytrium limacinum (Thraustochytriaceae, Labyrinthulomycota).  Mycoscience 46(6): 358-363

Short F.T., Mathieson, A.C. and Nelson J.I. (1986): Recurrence of the eelgrass wasting disease at the border of New Hampshire and Maine, U.S.A. Mar. Ecol. Prog.  Ser. 29: 89-92.

Short FT, Porter D, Iizumi H, Aioi K (1993) Occurrence of the eelgrass pathogen Labyrinthula zosterae in Japan.  Diseases of Aquatic Organisms 16: 73-77 <PDF>

Siegenthaler PA, Belsky MM, Goldstein S (1967) Phosphate Uptake in an Obligately Marine Fungus: A Specific Requirement for Sodium.  Science 155(3758): 93-94

Siegenthaler PA, Belsky MM, Goldstein S, Menna M (1967) Phosphate uptake in an obligately marine fungus. II. Role of culture conditions, energy sources, and inhibitors. J Bacteriol 93(4): 1281-1288  <PDF>

Sijtsma L, de Swaaf ME (2004) Biotechnological production and applications of the n-3 polyunsaturated fatty acid docosahexaenoic acid.  Appl Microbiol Biotechnol 64: 146–153

Singh A., Ward O. P. (1996) Production of high yields of docosahexaenoic acid by Thraustochytrium roseum ATCC 28210. Journal of Industrial Microbiology 16: 370-373

Singh A, Ward OP (1997) Microbial production of docosahexaenoic acid (DHA, C22:6).  Adv Appl Microbiol 45: 271–312

Singh A, Wilson S, Ward OP (1996) Docosahexaenoic acid (DHA) production by Thraustochytrium sp. ATCC20892.  J Microbiol Biotechnol 12: 76–83

Smolowitz R, Leavitt D, Perkins F (1998) Observations of a protistan disease similar to QPX in Mercenaria mercenaria (hard clams) from the coast of Massachusetts.  J Invertebr Pathol 71: 9–25

Sogin ML, Morrison HG, Hinkle G, Silberman JD (1996) Ancestral relationships of the major eukaryotic lineages. Microbiologia 12(1): 17-28

Song X, Zhang X, Guo N, Zhu L, Kuang C (2007) Assessment of marine thraustochytrid Schizochytrium limacinum OUC88 for mariculture by enriched feeds. Fish Sci 73: 565–573

Song X, Zhang X, Kuang C, Zhu L, Guo N (2007) Optimization of fermentation parameters for the biomass and DHA production of Schizochytrium limacinum OUC88 using response surface methodology.  Process Biochemistry 42(10): 1391-1397

Song X, Zhang X, Zhu L (2007) Studies on the DHA enrichment of rotifer with Schizochytrium limanium.  Marine Science (Qingdao) 31(12): 46-51

Solomon D, Sher S, Bell E (1978) The Motility of the Cells and the Extracellular Matrix of Labyrinthula -- A Colonial Organism Found on Zostera Marina.  Oceans 1984.  10: 99-104  <Link>

Sparrow FK (1936) Biological observations on the marine fungi of Woods Hole waters. Biological Bulletin 70: 236-263

Sparrow FK (1943) The aquatic Phycomycetes, Exclusive of the Saprolegniaceae and Pythium. Univ. of Michigan Press, Ann Arbor

Sparrow FK (1960) The aquatic Phycomycetes 2nd ed. Exclusive of the Saprolegniaceae and Pythium. Univ. of Michigan Press, Ann Arbor

Sparrow FK (1969) Zoosporic marine fungi from the Pacific Northwest (U. S. A.). Arch Mikrobiol 66: 129-146

Sparrow F.K. (1973):Mastigomycotina (zoosporic Fungi). In: Ainsworth G.C., Sparrow F.K. and Sussman A.S. (eds.): The Fungi, An Advanced Treatise. Vol. IV B . pp. 64-73. Academic Press,New York.

Stark KD, Lim SY, Salem N (2007) Artificial rearing with docosahexaenoic acid and n-6 docosapentaenoic acid alters rat tissue fatty acid composition. J Lipid Res 48(11): 2471-2477

Stey H (1968) [Reactions of hydryl anions, IV. Demonstration of a hitherto unknown organelle in Labyrinthula] Z Naturforsch B 23(4): 567

Stey H (1969) [Electron microscopic study of the Labyrinthula coenocystis Schmoller] Z Zellforsch Mikrosk Anat 102(3): 387-418

Stillwell W, Wassall SR (2003) Docosahexaenoic acid: membrane properties of a unique fatty acid.  Chem Phys Lipids 126: 1–27

Stoeck T, Taylor GT, Epstein SS (2003) Novel eukaryotes from the permanently anoxic cariaco basin (Caribbean Sea).  Applied and Environmental Microbiology 69: 5656-5663.

Stokes NA, Ragone Calvo LM, Reece KS, Burreson EM (2002) Molecular diagnostics, field validation, and phylogenetic analysisof Quahog Parasite Unknown (QPX), a pathogen of the hard clam Mercenaria mercenaria.  Dis Aquat Org 52: 233-247

Sumathl JC, Raghukumar S, Kasbekar DP, Raghukumar C (2006) Molecular Evidence of Fungal Signatures in the Marine Protist Corallochytrium limacisporum and its Implications in the Evolution of Animals and Fungi.  Protist 157(4): 363-376  <Link>

Sutherland IW (1998) Novel and established applications of microbial polysaccharides.  Trends Biotechnol 16: 41–46

Swofford DL (2003) PAUP*: Phylogenetic analysis using parsimony (* and other methods), version 4.0b 10. Sinauer Associates, Sunderland


Takao Y, Mise K, Nagasaki K, Okuno T, Honda D (2006) Complete nucleotide sequence and genome organization of a single-stranded RNA virus (SssRNAV) infecting the marine fungoid Schizochytrium sp. J Gen Virol 87: 723–733  <PDF>

Takao Y, Nagasaki K, Honda D (2007) Squashed ball-like dsDNA virus infecting a marine fungoid protist Sicyoidochytrium minutum (Thraustochytriaceae, Labyrinthulomycetes).  Aquat Microb Ecol  49: 101-108  <PDF>

Takao Y, Nagasaki K, Mise K, Okuno T, Honda D (2005) Isolation and characterization of a novel single-stranded RNA virus infectious to a marine fungoid protist, Schizochytrium sp. (Thraustochytriaceae, Labyrinthulea).  Appl Environ Microbiol 71: 4516–4522  <PDF>

Takao Y, Tomaru Y, Nagasaki K, Sasakura Y, Yokoyama R, Honda D. (2007) Fluorescence in situ hybridization using 18S rRNAtargeted probe for specific detection of thraustochytrids (Labyrinthulomycetes).  Plankton & Benthos Research 2: 91-97.

Taoka Y, Nagano N, Okita Y, Izumida H, Sugimoto S, Hayashi M (2008) Effect of addition of Tween 80 and potassium dihydrogenphosphate to basal medium on the isolation of marine eukaryotes, thraustochytrids.  J Biosci Bioeng 105(5): 562-565 <Link>

Taoka Y, Nagano N, Okita Y, Izumida H, Sugimoto S, Hayashi M (2009) Extracellular Enzymes Produced by Marine Eukaryotes, Thraustochytrids.  Bioscience, Biotechnology, and Biochemistry 73: 180-182 <PDF>

Teal TH, Guillemette T, Chapman M, Margulis L (1998) Acronema sippewissettensis Gen. Nov. Sp. Nov., microbial mat bicosoecid (Bicosoecales = Bicosoecida).  Eur J Protistol 34(4): 402-414

Thompson JD, Higgins DC, Gibson TJ (1994) Clustal W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position, specific gap penalties and weight matrix choice. Nucl Acids Res 22: 4673-4680

Tripodi KE, Buttigliero LV, Altabe SG, Uttaro AD (2006) Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan. FEBS J 273(2): 271-280

Tsui CKM, Marshall W, Yokoyama R, Honda D, Lippmeier JC, Craven KD, Peterson PD, Berbee ML (2009) Labyrinthulomycetes phylogeny and its implications for the evolutionary loss of chloroplasts and gain of ectoplasmic gliding.  Molecular Phylogenetics and Evolution 50: 129-140


Ulken A (1966) Untersuchungen uber marine Pilze im aquatorialen Alantik vor der Kuste Brailiens. Veroff. Inst.Meeresforsch. Bremerh. 10,107-116.

Ulken A (1968) Uber Zwei marine niedere Pilze vom Meeresboden der Nordsee. Veroff. Inst. Meeresforsch. Bremerh. Suppl. 3, 71-74.

Ulken A (1979b) Phycomycetenfunde in der Sargassosee. Veroff. Inst. Meeresforsch. Bremerh. 18, 21-27.

Ulken A (1981) On the role of phycomycetes in the food of different mangrove swamps with brackish waters of high salinity. Kieler Meeresforsch. Sonderh. 5: 425-428.

Ulken A. (1986): Estimation of thraustochytrid propagules in two mangrove swamps. Bot. Mar. 29, 85-89.

Ulken A, Jaeckle I, Bahnweg G (1985) Morphology, nutrition and taxonomy of an Aplanochytrium sp. from the Sargasso Sea.  Mar Biol 85: 89--95

Ulken A., Viquez R., Valiente C. and Campos M. (1990): Marine fungi (Chytridiomycetes and Thraustochytriales) from a mangrove area at Punta Morales, Golfo de Nicoya, Costa Rica. Revista de Biologia  Tropical, 243-250.

Unagul P, Assantachai C, Phadungruengluij S, Pongsuteeragul T, Suphantharika M, Verduyn C (2006) Biomass and docosahexaenoic acid formation by Schizochytrium mangrovei Sk-02 at low salt concentrations.  Botanica Marine 49(2): 182-190

Unagul P, Assantachai C, Phadungruengluij S, Suphantharika M, Tanticharoen M, Verduyn C (2007) Coconut water as a medium additive for the production of docosahexaenoic acid (C22:6 n3) by Schizochytrium mangrovei Sk-02.  Bioresour Technol 98(2): 281-287

Unagul P, Assantachai C, Phadungruengluij S, Suphantharika M, Verduyn C (2005) Properties of the docosahexaenoic acid-producer Schizochytrium mangrovei Sk-02: effects of glucose, temperature and salinity and their interaction.  Botanica Marina 48: 387-394


Valadon LRG (1976) Carotenoids as additional taxonomic characters in fungi: a review.  Trans Br Mycol Soc 67: 1-15

Valencia I, Ansorena D, Astiasaran I (2007) Development of dry fermented sausages rich in docosahexaenoic acid with oil from the microalgae Schizochytrium sp.: Influence on nutritional properties, sensorial quality and oxidation stability.  Food Chemistry 104(3): 1087-1096

van Beelen VA, Roeleveld J, Mooibroek H, Sijtsma L, Bino RJ, Bosch D, Rietjens IM, Alink GM (2007) A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells.  Food Chem Toxicol 45(5): 716-724

Vergeer LHT, den Hartog C (1994) Omnipresence of Labyrinthulaceae in seagrasses.  Aquat. Bot. 48: 1-20

Vishniac HS (1955) The nutritional requirements of isolates of Labyrinthula spp.  J Gen Microbiol 12(3): 455-463  <PDF>

Vishniac HS (1955) The activity of steroids as growth factors for a Labyrinthula sp.  J Gen Microbiol 12(3): 464-472 <PDF>

Vishniac HS (1957) The occurrence of cholesterol in Labyrinthula.  Biochim Biophys Acta 26(2): 430-431

Vishniac HS, Watson SW (1953) The steroid requirements of Labyrinthula vitellina var. pacifica. J Gen Microbiol 8(2): 248-255 <PDF>

Van de Peer Y, De Wachter R (1997) Evolutionary relationships among the eukaryotic crown taxa taking into account site-to-site rate variation in 18S rRNA. J Mol Evol 45(6): 619-630

Van de Peer Y, Van der Auwera G, De Wachter R (1996) The evolution of stramenopiles and alveolates as derived by "substitution rate calibration" of small ribosomal subunit RNA. J Mol Evol 42(2): 201-210


Wagner-Merner BT, Duncan WR, Lawrence JM (1980) Preliminary comparison of Thraustochytriaceae in the guts of a regular and irregular echinoid.  Bot. Mar. 23: 95-97

Wahid MI, Bitoon SR, Fukunaga T, Yoshikawa T, Sakata T (2008) Comparative study of leucine aminopeptidases from marine labyrinthulid and thraustochytrid strains.  Mem. Fac. Fish. Kagoshima Univ., Special Issue 26-33 <PDF>

Wahid MI, Yoshikawa T, Sakata T (2007) Bacteriolytic activity and growth of marine isolates of labyrinthulids on dead bacterial cells.  Fisheries Science (Tokyo) 73(6): 1286-1294

Wahid MI, Yoshikawa T, Sakata T (2008) Purification and characterization of leucine aminopeptidase from marine labyrinthulid strain 00-Bat-05.  Suisan Zoshoku 56: 1-8

Wallis JG, Watts JL, Browse J (2002) Polyunsaturated fatty acid synthesis: what will they think of next? Trends Biochem Sci 27:467–473

Ward OP, Singh A (2005) Omega-3/6 fatty acids: alternative sources of production.  Process Biochem 40:3627–3652

Watanabe K, Nakahara T, Yokochi T, Mohara S, Yazawa K (2000) Production of 13C-Labeled Docosahexaenoic Acid by a Thraustochytrid.  Journal of Japan Oil Chemists' Society 49: 1437-1442 <Link>

Watson SW, Ordal EJ (1957) Techniques for the isolation of Labyrinthula and Thraustochytrium in pure culture. J Bacteriol 73(4): 589-590

Watson SW, Raper KB (1957) Labyrinthula minuta n. sp.  J Gen Microbiol 17: 368–377 <PDF>

Weete JD, Kim H, Gandhi SR, Wang Y, Dute R (1997) Lipids and ultrastructure of Thraustochytrium sp. ATCC 26185.  Lipids 32(8): 839-845

Wethered JM, Jennings DH (1985) Major solutes contributing to solute potential of Thraustochytrium aureum and T. roseum after growth in media of different salinities.  Trans Br Mycol Soc 85: 439-446

Whyte SK, Cawthorn RJ, McGladdery SE (1994) QPX (Quahaug Parasite X), a pathogen of northern quahaug Mercenaria mercenaria from the Gulf of St. Lawrence, Canada.  Dis Aquat Org 19: 129–136

Wong MK, Tsui CK, Au DW, Vrijmoed LL (2008) Docosahexaenoic acid production and ultrastructure of the thraustochytrid Aurantiochytrium mangrovei MP2 under high glucose concentrations.  Mycoscience 49(4): 266-270

Wong MKM, Vrijmoed LLP, Au DWT (2005) Abundance of thraustochytrids on fallen decaying leaves of Kandelia candel and mangrove sediments in Futian National Nature Reserve, China.  Botanica Marina 48: 374–378

Wu ST, Yu ST, Lin LP (2005) Effect of culture conditions on docosahexaenoic acid production by Schizochytrium sp. S31.  Process Biochemistry 40(9): 3103-3108

Wu ST, Lin LP (2002) Production of Docosahexaenoic Acid and Succinic Acid by Schizochytrium sp. S31.  Food Science and Agricultural Chemistry 4: 62-66

Wu ST, Lin LP (2003) Application of Response Surface Methodology to Optimize Docosahexaenoic Acid Production by Schizochytrium sp. S31.  Journal of Food Biochemistry 27: 127-140

Wu K, Chai X (2003) Study on oxidative stability of lipid of Thraustochytrium roseum.  Chinese Journal of Marine Drugs 22: 34-37

Wu K, Chai X, Yang L (2003) [Effects of phytohormones on growth and DHA production by Thraustochytrium roseum] Wei Sheng Wu Xue Bao 43(1): 111-115



Yaguchi T, Tanaka S, Yokochi T, Nakahara T, Higashihara T (1997) Production of high yields of docosahexaenoic acid by Schizochytrium sp. strain SR21. J Am Oil Chem Soc 74:1431–1434

Yamaoka Y, Carmona ML, Jin K (2005) Blue light induces arsenate uptake in the protist Thraustochytrium.  Applied Organometallic Chemistry 19(2): 260-264 <Link>

Yamaoka Y, Carmona ML, Oota S (2004) Grouwth and carotenoid production of Thraustochytrium sp. CHN-1 cultured under superbright red and blue light-emitting diodes. Biosci Biotechnol Biochem 68: 1594-1597

Yamasaki T, Aki T, Mori Y, Yamamoto T, Shinozaki M, Kawamoto S, Ono K (2007) Nutritional enrichment of larval fish feed with thraustochytrid producing polyunsaturated fatty acids and xanthophylls. J Biosci Bioeng 104(3): 200-206

Yamasaki T, Aki T, Shinozaki M, Taguchi M, Kawamoto S, Ono K (2006) Utilization of Shochu distillery wastewater for production of polyunsaturated fatty acids and xanthophylls using thraustochytrid. J Biosci Bioeng 102(4): 323-327

Yang HL, Lu CK, Chen SF, Chen YM, Chen YM (2009) Isolation and Characterization of Taiwanese Heterotrophic Microalgae: Screening of Strains for Docosahexaenoic Acid (DHA) Production. Mar Biotechnol (NY) (in press)

Yokochi T, Honda D, Higashihara T, Nakahara T (1998) Optimization of docosaheaenoic acid production by Schizochytrium limacinum SR21. Appl Microbiol Biotechnol 49:72–76

Yokochi T, Nakahara T (2001) Diversity of Labyrinthulomycota and polyunsaturated fatty acids production.  Aquabiology 23: 39-45 (in Japanese)

Yokochi T, Nakahara T, Higashihara T, Yamaoka M, Kurane R (2001) A New Isolation Method for Labyrinthulids Using a Bacterium, Psychrobacter phenylpyruvicus.  Mar Biotechnol 3: 68-73

Yokoyama R, Honda D (2007) Taxonomic rearrangement of the genus Schizochytrium sensu lato based on morphology, chemotaxonomic characteristics, and 18S rRNA gene phylogeny (Thraustochytriaceae, Labyrinthulomycetes): emendation for Schizochytrium and erection of Aurantiochytrium and Oblongichytrium gen. nov.  Micoscience 48: 199-211.

Yokoyama R, Salleh B, Honda D (2007) Taxonomic rearrangement of the genus Ulkenia sensu lato based on morphology, chemotaxonomical characteristics, and 18S rRNA gene phylogeny (Thraustochytriaceae, Labyrinthulomycetes): emendation for Ulkenia and erection of Botryochytrium, Parietichytrium and Sicyoidochytrium gen. nov.  Micoscience 48: 329-341.

Yue CJ, Jiang Y (2009) Impact of methyl jasmonate on squalene biosynthesis in microalga Schizochytrium mangrovei.  Process Biochemistry 44(8): 923-927


Zhou L, Lu Y, Zhou M, Zhao X (2007) Enhanced Production of Docosahexaenoic Acid Using Schizochytrium sp. by Optimization of Medium Components.  Journal of Chemical Engineering of Japan 40(12): 1093-1100

Zhou MH, Zhou L, Zhao XW, Yu LJ, Lin N (2006) Separation and Identification of Schizochytrium sp.  Microbiology (Beijing) 33(4): 48-51

Zhu L, Zhang X, Ren X, Zhu Q (2008) Effects of Culture Conditions on Growth and Docosahexaenoic Acid Production from Schizochytrium limacinum.  Ocean University of China 7(1): 83-92

Zhu L, Zhang X, Ji L. Song X, Kuanga C (2007) Changes of lipid content and fatty acid composition of Schizochytrium limacinum in response to different temperatures and salinities.  Process Biochemistry 42: 210-214  <Link>

Zhukova NV, Kharlamenko VI (1999) Sources of essential fatty acids in the marine micorobial loop.  Aquat Microb Ecol 17: 153-157

Zinnai A, Nesti U, Venturi F, Andrich G, Fiorentini R (2006) Estrazione in fase supercritica di olio da Schizochytrium sp.  Rivista Italiana Delle Sostanze Grasse 83(1): 3-7

in Japanese

雪野 繼代 , 林 雅弘 , 井上 良計 , 今村 純子 , 長野 直樹 , 村田 寿(2005)ドコサヘキサエン酸富化スピルリナSpilurina platensisの調製と脂質特性.日本水産学会誌  71: 74-79